| No | Date | Activities | Place |
| 1 | Saturday 9 September | Side event (TBC) | Sheraton Hotel |
| 2 | Sunday, 10 September | APEC O2O Forum (Chinese Taipei) | Sheraton Hotel |
| 3 | Monday 11 September | Upgrading MSMEs Access to Finance in a Digital Age (Viet Nam) APEC Startup Forum (Viet Nam)* | Sheraton Hotel Reverie Saigon Hotel |
| 4 | Tuesday 12 September | APEC Digital Economy (United States) APEC Startup Forum (Viet Nam)* | Sheraton Hotel Reverie Saigon Hotel |
| 5 | Wednesday 13 September | SMEWG 45th Meeting (all day) | Sheraton Hotel |
| Welcome Dinner SMEWG 45th (Evening) | |
| 6 | Thursday 14 September | SMEWG 45th Meeting (Morning) | Sheraton Hotel |
| Field visit SMEWG 45th (Afternoon) | TBC |
| 7 | Friday 15 September | APEC SMEMM 25th (Morning) | Sheraton Hotel |
| APEC SMEMM 25th (Afternoon) APEC SMEMM 25th Press Conference(Afternoon) | Sheraton Hotel |